Basic Information
Gene ID ENSXETG00000020146
Gene Name ezh2
Full Name Histone-lysine N-methyltransferase EZH2
Organism Xenopus tropicalis [8364]

Cross Reference
UniProt F6SQP1 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSXETP00000043460 Pfam PF00856 IPR001214 642 712 4.70e-15 SET domain
ENSXETP00000043460 Pfam PF11616 IPR021654 42 71 7.60e-19 WD repeat binding protein EZH2
ENSXETP00000043460 ProSiteProfiles PS50280 IPR001214 572 713 0.00e-00 SET domain
ENSXETP00000043460 ProSiteProfiles PS51633 IPR026489 493 595 0.00e-00 CXC domain
ENSXETP00000043460 SMART SM00317 IPR001214 594 719 1.60e-21 SET domain
ENSXETP00000043460 SMART SM00717 IPR001005 162 240 5.80e-02 SANT/Myb domain
ENSXETP00000043460 SMART SM00717 IPR001005 418 466 1.90e-03 SANT/Myb domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSXETP00000043460 PF11616 2.4e-19 EZH2_WD-Binding WD repeat binding protein EZH2
ENSXETP00000043460 PF00856 4.7e-15 SET SET domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSXETP00000043460 GO:0006351 biological_process transcription, DNA-templated
ENSXETP00000043460 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSXETP00000043460 GO:0005634 cellular_component nucleus
ENSXETP00000043460 GO:0035098 cellular_component ESC/E(Z) complex
ENSXETP00000043460 GO:0003682 molecular_function chromatin binding
ENSXETP00000043460 GO:0018024 molecular_function histone-lysine N-methyltransferase activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100345157 30195 Bombus terrestris 100647736
9597 Pan paniscus 100971244 39432 Saimiri boliviensis 101051611
43179 Ictidomys tridecemlineatus 101968825 9358 Choloepus hoffmanni ENSCHOG00000013009
51511 Ciona savignyi ENSCSAVG00000002002 9361 Dasypus novemcinctus ENSDNOG00000013912
10020 Dipodomys ordii ENSDORG00000007731 9685 Felis catus ENSFCAG00000008618
9595 Gorilla gorilla ENSGGOG00000014846 59463 Myotis lucifugus ENSMLUG00000002498
9669 Mustela putorius furo ENSMPUG00000007249 9258 Ornithorhynchus anatinus ENSOANG00000000279
30611 Otolemur garnettii ENSOGAG00000010387 13735 Pelodiscus sinensis ENSPSIG00000014933
31033 Takifugu rubripes ENSTRUG00000015011 7029 Acyrthosiphon pisum 100168406
9823 Sus scrofa 100625497 132113 Bombus impatiens 100747000
10029 Cricetulus griseus 100758055 143995 Megachile rotundata 100883902
9555 Papio anubis 101001043 9031 Gallus gallus 420784
9615 Canis familiaris 475511 9598 Pan troglodytes 745437
28377 Anolis carolinensis ENSACAG00000013910 9483 Callithrix jacchus ENSCJAG00000016360
10141 Cavia porcellus ENSCPOG00000003710 8049 Gadus morhua ENSGMOG00000015628
9785 Loxodonta africana ENSLAFG00000001578 30608 Microcebus murinus ENSMICG00000011127
9544 Macaca mulatta ENSMMUG00000013494 13616 Monodelphis domestica ENSMODG00000001852
61853 Nomascus leucogenys ENSNLEG00000003596 9978 Ochotona princeps ENSOPRG00000007788
9601 Pongo abelii ENSPPYG00000018147 9305 Sarcophilus harrisii ENSSHAG00000017743
37347 Tupaia belangeri ENSTBEG00000015636 59729 Taeniopygia guttata ENSTGUG00000001770
99883 Tetraodon nigroviridis ENSTNIG00000001024 9478 Tarsius syrichta ENSTSYG00000000831
30538 Vicugna pacos ENSVPAG00000001437