===== Documentation =====
==== Data Input and Output ====
* SEQPower [[http://bioinformatics.org/spower/input|input]] data
* SEQPower simulation of [[http://bioinformatics.org/spower/write|association data]]
* SEQPower power analysis [[http://bioinformatics.org/spower/output|results]]
* [[http://bioinformatics.org/spower/benchmark#usage|Graphic representation]] of power calculation results
==== Complete List of Command Options ====
[[http://bioinformatics.org/spower/allargs|Argument list]]
==== Guide to Command Usage ====
=== Common options ===
* Genotype simulation options
* Phenotype simulation options
* Analysis options
* Association tests options
* Read more [[http://bioinformatics.org/spower/options|>>]]
=== Model specific options ===
* [[http://bioinformatics.org/spower/mlogit|LOGIT]] model
* [[http://bioinformatics.org/spower/mpar|PAR]] model
* [[http://bioinformatics.org/spower/mlnr|LNR]] model
* [[http://bioinformatics.org/spower/melnr|ELNR]] model
* [[http://bioinformatics.org/spower/mblnr|BLNR]] model
==== Genetic Sequences ====
* Population genetics model based simulation
* ''spower simulate'' command for forward time simulation of DNA sequences
* Data based simulation
* Direct sampling from real world data-set
* Read more [[http://bioinformatics.org/spower/simseq|>>]]
==== Disease Associations ====
=== Effects of variants ===
* Fixed effect vs. variable effects
* Protective, deleterious and neutral variants
* Read more [[http://bioinformatics.org/spower/simtraits|>>]]
=== Phenotype simulations ===
* Linear mean-shift model
* Extreme quantitative trait model
* Logit model of odds ratios
* Population attributable risk model
* Linear model with qualitative outcome
* Phenotype simulation for sequences drawn from haplotype pools
* Read more [[http://bioinformatics.org/spower/simtraits|>>]]
==== Power of Association Tests ====
* [[http://bioinformatics.org/spower/cc|Analytic power and sample size calculation for case control design]]
* [[http://bioinformatics.org/spower/qt|Analytic power and sample size calculation for quantitative traits design]]
* [[http://bioinformatics.org/spower/empirical|Empirical power and sample size calculations]]
==== Rare Variants Association Methods (RVAM) ====
* [[http://bioinformatics.org/spower/vat-methods|RVAM]] catalog
* [[http://bioinformatics.org/spower/benchmark|Power comparison for RVAM]]
==== Evaluating Novel Statistical Tests ====
* Writing [[http://bioinformatics.org/spower/vat-r|R extensions]]