===== Documentation ===== ==== Data Input and Output ==== * SEQPower [[http://bioinformatics.org/spower/input|input]] data * SEQPower simulation of [[http://bioinformatics.org/spower/write|association data]] * SEQPower power analysis [[http://bioinformatics.org/spower/output|results]] * [[http://bioinformatics.org/spower/benchmark#usage|Graphic representation]] of power calculation results ==== Complete List of Command Options ==== [[http://bioinformatics.org/spower/allargs|Argument list]] ==== Guide to Command Usage ==== === Common options === * Genotype simulation options * Phenotype simulation options * Analysis options * Association tests options * Read more [[http://bioinformatics.org/spower/options|>>]] === Model specific options === * [[http://bioinformatics.org/spower/mlogit|LOGIT]] model * [[http://bioinformatics.org/spower/mpar|PAR]] model * [[http://bioinformatics.org/spower/mlnr|LNR]] model * [[http://bioinformatics.org/spower/melnr|ELNR]] model * [[http://bioinformatics.org/spower/mblnr|BLNR]] model ==== Genetic Sequences ==== * Population genetics model based simulation * ''spower simulate'' command for forward time simulation of DNA sequences * Data based simulation * Direct sampling from real world data-set * Read more [[http://bioinformatics.org/spower/simseq|>>]] ==== Disease Associations ==== === Effects of variants === * Fixed effect vs. variable effects * Protective, deleterious and neutral variants * Read more [[http://bioinformatics.org/spower/simtraits|>>]] === Phenotype simulations === * Linear mean-shift model * Extreme quantitative trait model * Logit model of odds ratios * Population attributable risk model * Linear model with qualitative outcome * Phenotype simulation for sequences drawn from haplotype pools * Read more [[http://bioinformatics.org/spower/simtraits|>>]] ==== Power of Association Tests ==== * [[http://bioinformatics.org/spower/cc|Analytic power and sample size calculation for case control design]] * [[http://bioinformatics.org/spower/qt|Analytic power and sample size calculation for quantitative traits design]] * [[http://bioinformatics.org/spower/empirical|Empirical power and sample size calculations]] ==== Rare Variants Association Methods (RVAM) ==== * [[http://bioinformatics.org/spower/vat-methods|RVAM]] catalog * [[http://bioinformatics.org/spower/benchmark|Power comparison for RVAM]] ==== Evaluating Novel Statistical Tests ==== * Writing [[http://bioinformatics.org/spower/vat-r|R extensions]]