Table of Contents

Write Simulation Data Set to Files

The GroupWrite method can be used to save simulation data sets to separate files for purposes beyond the scope of SEQPower. See below for more details:

spower show test GroupWrite


It will create 3 files for each group:

If multiple replicates are specified, as the example below, the output dataset will be named with replicate ID as part of file name suffix.

Example

spower LOGIT KIT.gdat -a 1.5 --sample_size 2000 -P 0.8 --alpha 0.05 -v2 \
       --method "GroupWrite SimData" \
       -r 50 -j8


This command will result in files *_geno.txt, *_pheno.txt and *_mapping.txt recording simulated genotype, phenotype and variant map data.

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KIT_geno.txt
KIT:55524145	00	00	00	00	00	00	00	00	00
KIT:55524161	00	00	00	00	00	00	00	00	00
KIT:55561658	00	00	00	00	00	00	00	00	00
KIT:55561805	00	00	00	00	00	00	00	00	00
KIT:55561861	00	00	00	00	00	00	00	00	00
KIT:55564614	00	00	00	00	00	00	00	00	00
KIT:55564616	00	00	00	00	00	00	00	00	00
KIT:55570043	00	00	00	00	00	00	00	00	00
KIT:55570067	00	00	00	00	00	00	00	00	00
KIT:55589871	00	00	00	00	00	00	00	00	00
KIT:55592059	00	00	00	00	00	00	00	00	00
KIT:55592061	00	00	00	00	00	00	00	00	00
KIT:55593551	00	00	00	00	00	00	00	00	00
KIT:55593560	00	00	00	00	00	00	00	00	00
KIT:55593608	00	00	00	00	00	00	00	00	00
KIT:55598029	00	00	00	00	00	00	00	00	00
KIT:55598065	00	00	00	00	00	00	00	00	00
...


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KIT_pheno.txt
SAMP1	1
SAMP2	1
SAMP3	1
SAMP4	1
...
SAMP1997	0
SAMP1998	0
SAMP1999	0
SAMP2000	0


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KIT_mapping.txt
KIT	KIT:55524145
KIT	KIT:55524161
KIT	KIT:55561658
KIT	KIT:55561805
KIT	KIT:55561861
KIT	KIT:55564614
KIT	KIT:55564616
KIT	KIT:55570043
KIT	KIT:55592061
...


Recode genotypes

With the --recode switch genotypes are recoded to minor allele counts:

spower LOGIT KIT.gdat -a 1.5 --sample_size 2000 -P 0.8 --alpha 0.05 -v2 \
       --method "GroupWrite SimData --recode" \
       -r 50 -j8


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KIT_geno.txt
KIT:55524145	0	0	0	0	0	0	0	0	0
KIT:55524161	0	0	0	0	0	0	0	0	0
KIT:55561658	0	0	0	0	0	0	0	0	0
KIT:55561805	0	0	0	0	0	0	0	0	0
KIT:55561861	0	0	0	0	0	0	0	0	0
KIT:55564614	0	0	0	0	0	0	0	0	0
KIT:55564616	0	0	0	0	0	0	0	0	0
KIT:55570043	0	0	0	0	0	0	0	0	0
KIT:55570067	0	0	0	0	0	0	0	0	0
KIT:55589871	0	0	0	0	0	0	0	0	0
KIT:55592059	0	0	0	0	0	0	0	0	0
KIT:55592061	0	0	0	0	0	0	0	0	0
KIT:55593551	0	0	0	0	0	0	0	0	0
KIT:55593560	0	0	0	0	0	0	0	0	0
KIT:55593608	0	0	0	0	0	0	0	0	0
KIT:55598029	0	0	0	0	0	0	0	0	0
KIT:55598065	0	0	0	0	0	0	0	0	0
...