We've created perl scripts to submit large numbers of blast searches and also look for new hit in the output. See BSU and BSO at http://athena.bioc.uvic.ca/genomes/ -- Chris Upton PhD Associate Professor Biochemistry and Microbiology Phone 250-721-6507 University of Victoria PO Box 3055 Victoria Fax 250-721-8855 BC V8W 3P6, Canada http://web.uvic.ca/~cupton