[BiO BB] CMSB03 - deadline approaching
Michela de Concini
concini at brenta.dit.unitn.it
Tue Oct 22 05:58:13 EDT 2002
Computational Methods in Systems Biology
University of Trento
24-26 February, 2003 Rovereto, Italy
www.science.unitn.it/~priami/cmsb.html
Molecular biology has until now mainly focussed on individual
molecules, on their properties as isolated entities or as complexes
in very simple model systems. However, biological molecules in living
systems participate in very complex networks, including regulatory
networks for gene expression, intracellular metabolic networks and
both intra- and intercellular communication networks. Such networks
are involved in the maintenance (homeostasis) as well as the
differentiation of cellular systems of which we have a very
incomplete understanding.
Nevertheless, the progress of molecular biology has made possible the
detailed description of the components that constitute living
systems, notably genes and proteins. Large scale genome sequencing
means that we can (at least in principle) delimneate all
macromolecular components of a given cellular system, and microarray
experiments as well as large scale proteomics will soon give us large
amounts of experimental data on gene regulation, molecular
interactions and cellular networks. The challenge of the 21st century
will be to understand how these individual components integrate to
complex systems and the function and evolution of these systems, thus
scaling up from molecular biology to systems biology. By combining
experimental data with advanced formal theories from computer
science, "the formal language for biological systems" to specify
dynamic models of interacting molecular entities would be essential
for
1. understanding normal behaviour of cellular processes, and how
changes may affect the processes and cause disease. It may be
possible to correlate genetic properties and symptoms in new and more
efficient ways, based on an actual understanding of how various
processes interact.
2. Providing predictability and flexibility to academic,
pharmaceutical, biotechnology and medical researchers studying gene
or protein functions. In particular, it may save time by reducing the
number of experiments needed, if inadequate hypotheses could be
excluded by computer simulation.
Topics of interest include, but are not limited to:
Modelling languages for Systems Biology
Concurrency theory in Systems Biology
Constraint programming in Systems Biology
Logical methods in Systems Biology
Formal methods to analyse biomolecular systems
Quantitative analysis of biomolecular systems
Simulation techniques for Systems Biology
Case studies
IMPORTANT DATES
Nov 9, 2002 Submission deadline for papers and demos
Nov 30, 2002 Notification of acceptance
Dec 16, 2002 Camera-ready version due
PROCEEDINGS
The proceedings will be published in the Springer LNCS series and
will be available at the workshop.
SUBMISSION
Authors are invited to submit .ps or .pdf original research papers as
well as survey or tutorial papers of no more than 12 pages in LNCS
format (see
http://www.springer.de/comp/lncs/authors.html
for instructions) at the address
concini at dit.unitn.it
For further information please contact us at the addresses
[concini,priami]@dit.unitn.it. The papers will pass a peer review
process and the accepted ones will appear in the proceedings.
INVITED SPEAKERS
Ehud Shapiro, Weizmann Institute of Science, Israel
To be announced
PROGRAMME COMMITTEE
Charles Auffray, CNRS, Villejuif (F)
Cosima Baldari, Università di Siena (I)
Alexander Bockmayr, Université Henri Poincaré, Nancy (F)
Luca Cardelli, Microsoft Research Cambridge (UK)
Vincent Danos, Université Paris VII (F)
Pierpaolo Degano, Università di Pisa (I)
François Fages, INRIA Rocquencourt (F)
Drabløs Finn, , Norwegian University of Science and Technology, Trondheim (N)
Monika Heiner, Brandenburg University of Technology at Cottbus - (D)
Ina Koch, University of Applied Sciences Berlin, (D).
John E. Ladbury, University College London (UK)
Patrick Lincoln, SRI (USA)
Satoru Miyano, University of Tokyo (JP)
Gordon Plotkin, University of Edinburgh (UK)
Simon Plyte, Pharmacia Corporation (I)
Corrado Priami (CHAIR), Università di Trento (I)
Aviv Regev, Weizmann Institute of Science (IL)
Magali Roux-Rouquié, BSMI Pasteur Institute (F)
Vincent Schachter, Hybrigenics Paris (F)
Masaru Tomita, Keio University (JP)
Adelinde Uhrmacher, University of Rostock (D)
Alfonso Valencia, CNB-CSIC Centro Nacional de Biotecnologia,
Cantoblanco Madrid, (E)
Olaf Wolkenhauer, UMIST, Manchester (UK)
ORGANIZING COMMITTEE
Linda Brodo, Michela de Concini, Corrado Priami, Debora Schuch da Rosa Machado
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