[BiO BB] hi
Rong Chen
rong at bu.edu
Tue Jan 6 12:30:55 EST 2004
Hi Pankaj,
DS Protein Family in DS Modeling may be helpful. Check this web site:
http://www.accelrys.com/dstudio/ds_modeling/.
Rong
On Tue, 6 Jan 2004, Pankaj wrote:
> hi all,
> i m a new member of this board.
> i have a 3 protein structures (all taking the same fold) with the
> substrate bound. the residues surrounding the substrate are the active
> site residues. now i have a set of 400 protein sequences which i know
> take the same above mentioned fold. i want to extract the active site
> residues from these 400 sequences. but whatever alignment program i
> use either uses only sequence information or only structure
> information. is there an alignment program which can use both
> structure and sequence information for the alignment of these 400
> sequences on the strcutural template
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