[BiO BB] Question about selection in evolution

[Dan Bolser]

On Tue, 19 Apr 2005, Daniel Amelang wrote:

>
>>Does anyone know what kinds of genes that underwent positive selection the
>>most?
>>Could you also refer me some related paper about gene evolution?
>>  
>>
>The other day I was playing around with some software that determines 
>the level of positive/negative selection at the amino acid level for a 
>given gene. Perhaps it would help. It's called TreeSAAP
>
>http://inbio.byu.edu/faculty/dam83/cdm/
>
>Here's the paper introducing it:
>
>http://bioinformatics.oupjournals.org/cgi/content/abstract/19/5/671
>
>Although it may be more fine-grained that what you need, you could 
>theoretically use it to determine if a gene underwent positive selection 
>or not. TreeSAAP will tell you where in the sequence the selection 
>occured and for what amino acid property. Sounds like more that you need 
>:) Hey, it was worth mentioning.
>
>Dan

Hey! We need another Dan to form "The three Dans"!

Try googling for 'codon volatility'. It is one hypothetical measure of
selection pressure.


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