[BiO BB] KEGG vs GO

lucifer at slimy.greenend.org.uk lucifer at slimy.greenend.org.uk
Tue Apr 4 12:46:43 EDT 2006


"Samantha Fox" <bioinfosm at gmail.com> writes: 

> I was wondering how KEGG and GO differ from a broad perspective of 
> grouping functionally related genes.  So a KEGG pathway lists all genes 
> that kind of work together, and a similar GO term would also contain such > a gene list.

IIRC, KEGG is manually created from the literature whilst GO also contains 
automatic/electronic annotation based on sequence homology.  KEGG also 
focuses more on metabolic pathways, whilst GO covers a more comprehensive 
set of cellular processes and molecular functions. 


Hope that helps,
Lucy 

 --
Lucy McWilliam
http://www.chiark.greenend.org.uk/~lucifer/ 




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