[BiO BB] KEGG vs GO
dmb at mrc-dunn.cam.ac.uk
Wed Apr 5 06:13:14 EDT 2006
lucifer at slimy.greenend.org.uk wrote:
> "Samantha Fox" <bioinfosm at gmail.com> writes:
>> I was wondering how KEGG and GO differ from a broad perspective of
>> grouping functionally related genes. So a KEGG pathway lists all
>> genes that kind of work together, and a similar GO term would also
>> contain such > a gene list.
> IIRC, KEGG is manually created from the literature whilst GO also
> contains automatic/electronic annotation based on sequence homology.
> KEGG also focuses more on metabolic pathways, whilst GO covers a more
> comprehensive set of cellular processes and molecular functions.
> Hope that helps,
It should be possible to 'cross correlate' KEGG an GO in a number of
different ways using one of the SWISSPROT relational databases. However
you should know that generally 'ontology mapping' is an open problem :)
> Lucy McWilliam
> Bioinformatics.Org general forum - BiO_Bulletin_Board at bioinformatics.org
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