[BiO BB] Tiling microarray

Ann Loraine aloraine at gmail.com
Tue Feb 21 16:00:05 EST 2006


This is a just a guess, I'm afraid, but quantile-quantile
normalization is probably a good way to go.

For visualizing tiling array data, I recommend using the Integrated
Genome Browser. It lets you do things like load tiling array data as
simple text files with position/value pairs and then perform simple
manipulations, such as subtracting one graph from another.

There are some links from my Web site http://www.transvar.org
including a now slightly out-of-date tutorial
(http://www.transvar.org/at_annots) that might be useful. Also, you
should check out http://genoviz.sourceforge.net. That will take you to
a Java Web Start page at Affymetrix where you can download and launch
the program.

All the best,

Ann Loraine

On 2/21/06, Che, Anney (NIHNIAID) <chea at mail.nih.gov> wrote:
> Hi,
>
> Does anyone know how to normalize Tiling microarray data?
> And any good software that analysis tiling microarray data.
>
> Thanks,
>
> Anney
> --
> Anney Che, M.S.
> Biocomputing Specialist
> Laboratory of Molecular Microbiology (LMM)
> National Institute of Allergy and Infectious Diseases (NIAID)
> 9000 Rockville Pike, Bldg 4, Room 301
> Bethesda, MD 20892
> Phone: 301-451-2851
> Fax: 301-280-2716
>
>
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>


--
Ann Loraine
Assistant Professor
Section on Statistical Genetics
University of Alabama at Birmingham
http://www.ssg.uab.edu
http://www.transvar.org



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