Great to see lots of new subscribers to the list _and_ a great thread. I think this list is starting to reach critical mass. Three things: (1) My limited experience with MOSIX has me believing that in the MOSIX world a process that is doing heavy I/O operations will never get migrated across to a less loaded machine. This alone is enough for me to not consider MOSIX/SSI for bioclusters because all of the ones I have built so far are very, very often used for IO-bound embarassingly parallel jobs (blast, genscan, etc. etc). Am I totally wrong? Anyone out there using SSI/Mosix systems for hardcore biology stuff? (2) Diskless. I would never _not_ put a large cheap IDE drive in my cluster elements because at the very least I need a local large /tmp or /scratch partition for caching sequence databases and raw data. Without this approach you pretty much will swamp your NFS server under any sort of serious workload. Diskless I guess would be cool for limited-scope systems that will only be doing crazy MPI/PVM or CPU-bound jobs. Anyone doing this? Also much of the benefits touted by proponants of diskless clusters such as ease of cluster management and ease of OS image management go away if you use something like SystemImager or the FAI scripts that were referred to in a previous email. Are there any other advantages to diskless clusters that people have seen for real world life science computing? Ram disks? (3) BIOITWORLD Roll Call Anyone coming to Boston for the IDG BioITWorld conference? I was supposed to organize the biocluster BOF along with Andrew Fant, Glen Otero and Jeff Bizzaro but it looks as though I'm going to be on the west coast that week. Glen, Jeff & Andy will run the BOF without me and we'll post the details to this list once we have them. Give a shout if you are coming to town. It would be nice to know how many list members will be in attendence. Also- any other conferences/workshops/meetings coming up that people recommend? -Chris -- Chris Dagdigian, <dag@sonsorol.org> Life Science IT & Research Computing Freelancer & member of the bioteam.net consulting collective Office: 617-666-6454, Mobile: 617-877-5498, Fax: 425-699-0193 Yahoo IM: craffi