[Bioclusters] Medical Device Investments, Mergers and Acquisitions for Q2 03

Venture Reporter bioclusters@bioinformatics.org
21 Jul 2003 14:55:28 -0000


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        <p>Excerpt from <em><a href="https://secure.risingtidestudios.com/getPDF/?c=PPG7P5EN&PromotionalCode=spiced" target="_blank" title="Opens in New Window.">Medical
              Device
                Investments, Mergers and Acquisitions for Q2 03</a></em>, available
            from <em>Venture Reporter</em> for $395</p>
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	    <TD class="subheading"><EM>Venture Reporter</EM>  looks at and
	      analyzes the trends highlighted by Q2 2003&#8217;s VC and M&amp;A deals
	      in the medical device industry.</TD>
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	    <TD><P align="justify"><span class="cap">S</span>ome very ugly numbers
	        on venture capital investing were released in the second quarter
	        of 2003, and medical device investing fell along with most other
	        sectors (fig. 1). Executives that announced deals in the second quarter
	        were,
	        for the most part, out raising capital during the first quarter (or
	        earlier) when the uncertainty of depressed public markets and looming
	        war with Iraq took a heavy toll on valuations, which likely explains
	        the lag time before VC investing truly reflected that market uncertainty
	        that took its toll on the public markets until Spring 2003. Its stands
	        to reason, then, that medical device investing might experience a
	        resurgence
	        in Q3 2003 as it enjoys the fruits of a well-performing healthcare
	        sector on the public equity side.<br>
</P>
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		<td bordercolor="FEFDED" bgcolor="FEFDED" class="graph-detail"><em><strong>Medical Devices Investments,	Mergers and Acquisitions for Q2 03<br>
		</strong></em> is available now from <em>Venture Reporter</em>.</td>
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	    <TD valign="top"><P align="justify"> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Between
	        April 1, 2003 and June 25, 2003, the Dow Jones Healthcare Index gained
	        about 10 percent, rising
	        from the April 1 close of 248.86 points to the June 25 close of 274.24
	        points. Over that same period, the Dow Jones Industrial Average gained
	        942 points &#8212; or
	        12 percent &#8212; making healthcare one of the poorer performing sectors
	        overall.<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Though VC investing fell off in the second quarter, M&amp;A activity picked up,
and Abbot Laboratories&#8217; $170 million acquisition of Texas-based Spinal
Concepts certainly added to the excitement that already surrounds spinal products
in the medical device sector.<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; As is generally the case in the healthcare industry, be it biotechnology or medical
technologies/devices, California and Massachusetts were well ahead of the pack
in number of investments received. Six California companies received venture
capital investment this quarter, or 43 percent of all medical device investments
in the second quarter (fig 6). California-located investments were worth an overall
total of $81.1 million, or 54 percent of the dollars invested in medical devices
this quarter. Even more impressive was the fact that the top five largest investments
in medical device companies in the second quarter were located in California:
CryoCor, Orqis Medical, Xoft microTube, St. Francis Medical Technologies and
Opus Medical. Massachusetts investments, of which there were four, were worth
a total of $30 million &#8212; 20 percent of all the dollars invested in medical
devices this quarter. The remaining deals were distributed across Washington
state (two investments) and non-U.S.-based companies (two investments). <br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; A majority of investors interviewed for this report,
when asked what their preferred sub-sector for investment was within the medical
device space, said that spine
was a particularly appealing area for investment. Ostensibly, this is</P>
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            <TD valign="top" bgcolor="#000000" class="graph-header"><DIV align="center"><font color="#FFFFFF">Medical
                  Device
                  Deals  by Quarter</font></DIV>
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              <table style="border-bottom:1px gray solid;margin-bottom:5px" width="175" height="125" border="0" cellpadding="0" cellspacing="0" background="http://venturereporter.net/media/q2med-fig1.gif" class="graph-detail">
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                  <td height="25"><div align="left"> </div>
                      <div align="left"></div>                      
                      <font color="#FFFFFF"><strong>&nbsp;&nbsp;&nbsp;</strong>Q2
                    02<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(27)</strong></font></td>
                </tr>
                <tr>
                  <td height="25"><strong>&nbsp;</strong><strong>&nbsp;&nbsp;</strong>Q3
                    02<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(20)</strong></td>
                </tr>
                <tr>
                  <td height="25"><strong><font color="#FFFFFF">&nbsp;</font></strong><font color="#FFFFFF"><strong>&nbsp;&nbsp;</strong>Q4
                    02<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(30)</strong></font></td>
                </tr>
                <tr>
                  <td height="25"><font color="#FFFFFF"><strong>&nbsp;&nbsp;&nbsp;</strong>Q1
                    03<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(31)</strong></font></td>
                </tr>
                <tr>
                  <td height="25"><strong>&nbsp;&nbsp;&nbsp;</strong>Q2
                    03<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;(14)</strong></td>
                </tr>
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                  <TD width="20" class="graph-detail"><DIV align="right"> <EM><strong>fig.1</strong></EM></DIV>
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            <TD valign="top" bgcolor="#000000" class="graph-header">
              <DIV align="center"><font color="#FFFFFF">Q2 03 Medical Device
                  Investments by Subsector</font></DIV>
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            <TD bordercolor="#FFFFFF" class="graph-detail"><TABLE   WIDTH="175" border="0" cellspacing="0" cellpadding="2">
                  <TR valign="top">
                   <TD class="graph-detail"> 
                    	<table style="border-bottom:1px gray solid;margin-bottom:5px" width="175" height="175" border="0" cellpadding="0" cellspacing="0" background="http://venturereporter.net/media/q2med-fig4.gif" class="graph-detail">
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                        		<td height="25"><div align="left"><strong> &nbsp;&nbsp;&nbsp;<font color="#FFFFFF">Cardiovascular
                       		        (4)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
                                              </font></strong></div></td>
                   		 </tr>
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                        		<td height="25"><div align="right"><strong>&nbsp;&nbsp;Cancer
                       		        (2)&nbsp;&nbsp;&nbsp;<font color="#FFFFFF"></font> </strong></div></td>
                   		 </tr>
                        	<tr>
                        		<td height="25"><div align="right"><strong>&nbsp;&nbsp;&nbsp;Spine
                        		      (2)&nbsp;&nbsp;&nbsp;<font color="#FFFFFF"></font></strong></div></td>
                   		 </tr>
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                        		<td height="25"><div align="right"><strong>Joint
                        		        (1)&nbsp;&nbsp;&nbsp;<font color="#FFFFFF"></font></strong></div></td>
                   		 </tr>
                        	<tr>
                        		<td height="25"><div align="right"><strong>Dialysis
                        		      (1)&nbsp;&nbsp;&nbsp;<font color="#FFFFFF"></font></strong></div></td>
                   		 </tr>
                        	<tr>
                        	  <td height="25"><div align="right"><strong>&nbsp;&nbsp;GERD
                        	        (1)&nbsp;&nbsp;&nbsp;<font color="#FFFFFF"></font></strong></div></td>
                      	  </tr>
                        	<tr>
                        	  <td height="25"><div align="right"><strong>Other (3)&nbsp;&nbsp;<font color="#FFFFFF"></font></strong></div></td>
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                   	    <div align="right"><EM><STRONG>fig.
                            	4</STRONG></EM>
                       	</div></TD>
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        			<DIV align="center"><font color="#FFFFFF">Medical Device</font><font color="#FFFFFF"> Investments,<br>
				Mergers and Acquisitions<br>
				PRICING OPTIONS</font></DIV>
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               <DIV align="center"><STRONG>1</STRONG></DIV>
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          <p>Excerpt from <em><a href="https://secure.risingtidestudios.com/getPDF/?c=PPG7P5EN&PromotionalCode=spiced" target="_blank" title="Opens in New Window.">Medical
                Device
                Investments, Mergers and Acquisitions for Q2 03</a></em>, available
                from <em>Venture Reporter</em> for $395</p>
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	    <TD height="35" valign="top"><SPAN class="subheading"><EM>(continued)</EM></SPAN></TD>
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	      <p>largely due to an aging baby-boomer population in need of relief for
	        aching backs in concert with recent high-profile acquisitions in the
	        spine area. Some investors indicated that a feeding frenzy is likely
	        to ensue whenever there are a number of acquisitions in a given sub-sector,
	        due to the near-closed public markets
for medical device companies.</p>
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        		<td bordercolor="FEFDED" bgcolor="FEFDED" class="graph-detail"><em><strong>Medical Devices Investments,	Mergers and Acquisitions for Q2 03<br>
        			</strong></em> is available now from <em>Venture Reporter</em>.</td>
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	    <TD valign="top"><P align="justify">	        &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Other investors were simply
	        bullish on the potential for new innovation as multiple technologies
	        converge in the healthcare sector &#8212; therapeutics, devices and
	        IT &#8212; to create new, innovative products that save patient time
	        and pain, payer cost and hospitalization. Dr. Tom Fogarty of Three Arch
	        Partners said, &#8220;If you have a service or an Internet connection
	        that makes [integrating the device] seamless, the patient doesn&#8217;t
	        have to call the technician, it represents a higher degree of acceptance
	        for the patient. I think these represent some real significant opportunities.&#8221;<br>
	      &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; San Diego, California-based CryoCor, a developer of cardiac cyrotherapy
	      technology that delivers deep freezing shots through a catheter into
	      the heart, helping to isolate arrhythmia-inducing tissue, raised the largest
	      medical device investment of the quarter. CryoCor raised $27.5 million
	      from Beecken Petty &amp; Company, Frantz Medical Ventures, Oakwood Medical
	      Investors, OrbiMed Advisors, Technology Partners and William Blair
	      Capital Partners. The company said it would apply the new funding towards
	      clinical
	      trials of its CryoCor Cardiac Cryoablation System, as well as toward
	      the development of new products. The investment will be dispersed in
	      two installments:
	      $15.3 million on June 4, 2003 and $12.2 million by June 2004. The technology
	      works by freezing heart tissue responsible for arrhythmia. A cold-tipped
	      catheter with a variable temperature setting allows the operating physician
	      to determine how much tissue must be killed to cure the patient. The
	      CryoCor investment demonstrates the trend toward venture capitalist
	      investment in minimally invasive alternatives to more involved surgical
	      procedures.&nbsp;		<span class="brown">&nbsp;&nbsp;&nbsp;&nbsp;</span>&nbsp;<font color="6f5e54"><strong>VR</strong></font></P>
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            <TD valign="top" bgcolor="#000000" class="graph-header" style="border-bottom:1px gray solid"><DIV align="center"><font color="#FFFFFF">Medical
                  Device Investments by Round, Q2 2003</font></DIV>
            </TD>
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            <TD bordercolor="#FFFFFF">
              <TABLE STYLE="table-layout: fixed" WIDTH="175" border="0" cellspacing="0" cellpadding="2">
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                    <DIV align="center"></DIV>
                    Seed</TD>
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                <TR valign="top">
                  <TD bgcolor="fefded" class="graph-detail" style="border-bottom:1px gray solid"><DIV align="right"> <STRONG>1
                        deals</STRONG><STRONG>&nbsp;</STRONG></DIV>
                  </TD>
                </TR>
                <TR valign="top" bgcolor="F4FAF6">
                  <TD bgcolor="#FFFFFF" class="graph-detail">
                    <DIV align="center"></DIV>
                    First</TD>
                </TR>
                <TR valign="top">
                  <TD class="graph-detail" style="border-bottom:1px gray solid"><DIV align="right"> <STRONG>3
                        deals</STRONG><STRONG>&nbsp;</STRONG></DIV>
                  </TD>
                </TR>
                <TR valign="top" bgcolor="F4FAF6">
                  <TD bgcolor="fefded" class="graph-detail">
                    <DIV align="center"></DIV>
                    Second</TD>
                </TR>
                <TR valign="top">
                  <TD bgcolor="fefded" class="graph-detail" style="border-bottom:1px gray solid"><DIV align="right"> <STRONG>3
                        deals</STRONG><STRONG>&nbsp;</STRONG></DIV>
                  </TD>
                </TR>
                <TR valign="top" bgcolor="F4FAF6">
                  <TD bgcolor="#FFFFFF" class="graph-detail">
                    <DIV align="center"></DIV>
                    Third</TD>
                </TR>
                <TR valign="top">
                  <TD class="graph-detail" style="border-bottom:1px gray solid"><DIV align="right"> <STRONG>1
                        deals</STRONG><STRONG>&nbsp;</STRONG></DIV>
                  </TD>
                </TR>
                <TR valign="top">
                  <TD bgcolor="fefded" class="graph-detail">Fourth and Up</TD>
                </TR>
                <TR valign="top">
                  <TD bgcolor="fefded" class="graph-detail" style="border-bottom:1px gray solid"><div align="right"><STRONG>3
                        deals</STRONG><STRONG>&nbsp;</STRONG></div>
                  </TD>
                </TR>
                <TR valign="top">
                  <TD class="graph-detail"><DIV align="right"> <EM><STRONG> fig.
                          5</STRONG></EM></DIV>
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        		<TD valign="top" bgcolor="#000000" class="graph-header" style="border-bottom:1px gray solid"><DIV align="center"><font color="#FFFFFF">Top Medical Device Acquisitions of	Q2 03</font></DIV>
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        						<DIV align="center"></DIV>
        						Invitrogen [NY]<br>
        						<em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;acquires...</strong></em></TD>
   					 </TR>
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        					<TD height="25" class="graph-detail" style="border-bottom:1px gray solid"><DIV align="right"> InforMax	[MD] for<strong> $42M</strong></DIV>
   						 </TD>
   					 </TR>
        				<TR valign="top" bgcolor="F4FAF6">
        					<TD class="graph-detail" style="border-bottom:1px gray dotted"> American Med. Systems [MN]<br>
            						<em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;acquires...</strong></em></TD>
   					 </TR>
        				<TR valign="top">
        					<TD height="25" class="graph-detail" style="border-bottom:1px gray solid"><DIV align="right">CryoGen	[CA] for <strong>$40M</strong></DIV>
   						 </TD>
   					 </TR>
        				<TR valign="top" bgcolor="F4FAF6">
        					<TD class="graph-detail" style="border-bottom:1px gray dotted"> Quinton Cardiology [WA]<br>
            						<em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;acquires...</strong></em></TD>
   					 </TR>
        				<TR valign="top">
        					<TD height="25" class="graph-detail" style="border-bottom:1px gray solid"><DIV align="right"> Spacelabs	Burdick [WA]<br>
							for <strong>$24M</strong></DIV>
   						 </TD>
   					 </TR>
        				<TR valign="top" bgcolor="F4FAF6">
        					<TD class="graph-detail" style="border-bottom:1px gray dotted"> Medical	Action Industries[NY]<br>
                   						<em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;acquires...</strong></em></TD>
   					 </TR>
        				<TR valign="top">
        					<TD height="25" class="graph-detail" style="border-bottom:1px gray solid"><DIV align="right">Biosafety	Division [WV] for <strong>$19.5M</strong> </DIV>
   						 </TD>
   					 </TR>
        				<TR valign="top">
        					<TD class="graph-detail"><DIV align="right"> <EM><STRONG> fig.	10</STRONG></EM></DIV>
   						 </TD>
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             <DIV align="center"><STRONG>2</STRONG></DIV>
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