Hi Nick, I've written about this in the past; you can find stuff in the list archives. Some of the articles and presentations I've done on "bioclusters" are linked off this URL: http://bioteam.net/dag/ - something there may be of use. In general I'd go with BioBrew or the ROCKS cluster kit ("roll") that comes with Grid Engine as the scheduler if you are starting out. If you want to roll your own cluster to have maximum flexibility and really learn the behind the scenes stuff just pick the "best" (or your favorite) componants to match the following requirements: 1. A Linux distribution 2. A Resource manager & scheduler software (Grid Engine, etc.) 3. Software for doing unattended "bare metal" installs and incremental updates (SystemImager, etc.) 4. Management & monitoring packages (ganglia, nagios, bigbrother, etc.) Take what you chose for #1-4 and put all the compute nodes on a private gigabit ethernet switch. There should be a common NFS share for user home directories and maybe for the scheduler system. Pick one node to be the "master" node and connect one of its NICs to the "private" cluster network and the 2nd NIC to the company/department network. This way you and your users only have to login to and deal with the one single "master" node. -Chris Nick D'Angelo wrote: > > All, > > I am sure this has been asked many times before, but what is the preferred > method or perhaps 'best' method of clustering a few 3-5 RedHat or other > Linux flavours to best suit our Bioinfo R and D group? > > I have come across biobrew with their own cd distribution install and also > this group. > > I was going to originally look at Fedora core 2, but that appeared to be > painful due to the kernel re-compile and to be honest, the documentation > appeared to be quite poor, at least what I found. > > Any suggestions? > > Thanks, -- Chris Dagdigian, <dag at sonsorol.org> BioTeam - Independent life science IT & informatics consulting Office: 617-665-6088, Mobile: 617-877-5498, Fax: 425-699-0193 PGP KeyID: 83D4310E iChat/AIM: bioteamdag Web: http://bioteam.net