Eric, Are the versions of Firefox the same on the computers? I have two WinXP PCs and I lost to ability with Firefox to load local files pdb and mol with my simple chime viewer; _http://expedioscientiam.net/molvis/_ (http://expedioscientiam.net/molvis/) It has not been a priority for me to get Firefox working right. However, I had wondered about whether versions changes in Firefox may be part of the problem. On seeing your note about problems. I decided to uninstall the current version of Firefox on my notebook pc. Then I installed version 1.0.1. In that version, I could load the local files. When I reinstalled 1.5, I lost the ability to load locally again. Later, Jeff In a message dated 7/23/2006 8:46:17 P.M. Eastern Standard Time, emartz at microbio.umass.edu writes: I have a vexing, persistent Chime/Firefox configuration problem that I hope someone can help me fix. THE PROBLEM On one of my computers (but none of the others), local .pdb files fail to display in Chime in Firefox.