[Molvis-list] For Workshop: Need Proteins with known struct and mutations
gilgonza88 at gmail.com
Thu Jun 11 10:50:54 EDT 2009
Dear Dr. Christoph Gille in my courses of biomoleculs and heterociclic
chemistry at the Universidad Nacional Autonoma de Mexico campus Cuauttitlan
and Iztacala we are interested in the proteins related to AH1N! virus
Hemaglutinin and Neuramidase.
Thanks a lot.
Secc. Quimica Organica
Departamento de Ciencias Quimicas
UNAM FES CUAUTITLAN
Modulo de Biomoleculas
UNAM FES IZTACALA
2009/6/11 Dr. Christoph Gille <christoph.gille at charite.de>
> For our Workshop next week we would like to ask you for your ideas about
> proteins with known 3D-structure, and known disease causing mutations.
> Next week we will give a practical workshop in Bioinformatics for
> postgraduate students of Molecular Medicine.
> Our plan is that each student chooses a protein. The students will
> obtain all mutations and SNPs from the literature and from databases.
> The students should then visualize the mutations on a homologous
> 3D-structure using the Pymol view (http://en.wikipedia.org/wiki/Pymol)
> integrated in STRAP ( http://3d-alignment.eu/ ).
> In the final presentation each student should discuss the function of
> his/her protein and how the mutation could affect its function in terms of
> catalysis, ligand binding, 3D-structure stability ... .
> Do you have ideas for proteins that would be appropriate?
> Many thanks
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