Basic Information
Gene ID 100058880
Gene Name MSX2
Full Name Uncharacterized protein
Organism Equus caballus [9796]

Cross Reference
UniProt F7AIQ4 UniGene NULL
PDB NULL OMIM NULL
KEGG ecb:100058880 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSECAP00000009591 Gene3D G3DSA:1.10.10.60 IPR009057 119 201 1.70e-25 Homeodomain-like
ENSECAP00000009591 Pfam PF00046 IPR001356 143 199 5.30e-22 Homeobox domain
ENSECAP00000009591 PRINTS PR00024 IPR020479 164 175 1.10e-06 Homeodomain, metazoa
ENSECAP00000009591 PRINTS PR00024 IPR020479 179 189 1.10e-06 Homeodomain, metazoa
ENSECAP00000009591 PRINTS PR00024 IPR020479 189 198 1.10e-06 Homeodomain, metazoa
ENSECAP00000009591 ProSitePatterns PS00027 IPR017970 175 198 - Homeobox, conserved site
ENSECAP00000009591 ProSiteProfiles PS50071 IPR001356 140 200 0.00e-00 Homeobox domain
ENSECAP00000009591 SMART SM00389 IPR001356 142 204 1.20e-27 Homeobox domain
ENSECAP00000009591 SUPERFAMILY SSF46689 IPR009057 121 201 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSECAP00000009591 PF00046 3.4e-22 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSECAP00000009591 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSECAP00000009591 GO:0001649 biological_process osteoblast differentiation
ENSECAP00000009591 GO:0002063 biological_process chondrocyte development
ENSECAP00000009591 GO:0002076 biological_process osteoblast development
ENSECAP00000009591 GO:0003148 biological_process outflow tract septum morphogenesis
ENSECAP00000009591 GO:0003198 biological_process epithelial to mesenchymal transition involved in endocardial cushion formation
ENSECAP00000009591 GO:0003416 biological_process endochondral bone growth
ENSECAP00000009591 GO:0006351 biological_process transcription, DNA-templated
ENSECAP00000009591 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSECAP00000009591 GO:0007275 biological_process multicellular organismal development
ENSECAP00000009591 GO:0008285 biological_process negative regulation of cell proliferation
ENSECAP00000009591 GO:0009952 biological_process anterior/posterior pattern specification
ENSECAP00000009591 GO:0023019 biological_process signal transduction involved in regulation of gene expression
ENSECAP00000009591 GO:0030513 biological_process positive regulation of BMP signaling pathway
ENSECAP00000009591 GO:0032792 biological_process negative regulation of CREB transcription factor activity
ENSECAP00000009591 GO:0035115 biological_process embryonic forelimb morphogenesis
ENSECAP00000009591 GO:0035116 biological_process embryonic hindlimb morphogenesis
ENSECAP00000009591 GO:0035313 biological_process wound healing, spreading of epidermal cells
ENSECAP00000009591 GO:0035880 biological_process embryonic nail plate morphogenesis
ENSECAP00000009591 GO:0042640 biological_process anagen
ENSECAP00000009591 GO:0043066 biological_process negative regulation of apoptotic process
ENSECAP00000009591 GO:0045599 biological_process negative regulation of fat cell differentiation
ENSECAP00000009591 GO:0045617 biological_process negative regulation of keratinocyte differentiation
ENSECAP00000009591 GO:0045669 biological_process positive regulation of osteoblast differentiation
ENSECAP00000009591 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSECAP00000009591 GO:0051795 biological_process positive regulation of catagen
ENSECAP00000009591 GO:0060346 biological_process bone trabecula formation
ENSECAP00000009591 GO:0060364 biological_process frontal suture morphogenesis
ENSECAP00000009591 GO:0060444 biological_process branching involved in mammary gland duct morphogenesis
ENSECAP00000009591 GO:0061312 biological_process BMP signaling pathway involved in heart development
ENSECAP00000009591 GO:0070166 biological_process enamel mineralization
ENSECAP00000009591 GO:0071363 biological_process cellular response to growth factor stimulus
ENSECAP00000009591 GO:0071392 biological_process cellular response to estradiol stimulus
ENSECAP00000009591 GO:0090427 biological_process activation of meiosis
ENSECAP00000009591 GO:2000678 biological_process negative regulation of transcription regulatory region DNA binding
ENSECAP00000009591 GO:2001055 biological_process positive regulation of mesenchymal cell apoptotic process
ENSECAP00000009591 GO:0005634 cellular_component nucleus
ENSECAP00000009591 GO:0005667 cellular_component transcription factor complex
ENSECAP00000009591 GO:0005737 cellular_component cytoplasm
ENSECAP00000009591 GO:0003677 molecular_function DNA binding
ENSECAP00000009591 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSECAP00000009591 GO:0003712 molecular_function transcription cofactor activity
ENSECAP00000009591 GO:0008134 molecular_function transcription factor binding
ENSECAP00000009591 GO:0043565 molecular_function sequence-specific DNA binding
ENSECAP00000009591 GO:0044212 molecular_function transcription regulatory region DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100026817 8090 Oryzias latipes 100049217
30195 Bombus terrestris 100649911 34638 Metaseiulus occidentalis 100900625
7460 Apis mellifera 724412 9315 Macropus eugenii ENSMEUG00000005940
7425 Nasonia vitripennis 100114980 10224 Saccoglossus kowalevskii 100303531
28377 Anolis carolinensis 100561295 61853 Nomascus leucogenys 100581634
400682 Amphimedon queenslandica 100631603 132113 Bombus impatiens 100741791
10029 Cricetulus griseus 100761249 143995 Megachile rotundata 100881753
9597 Pan paniscus 100987321 9555 Papio anubis 101008621
39432 Saimiri boliviensis 101033932 9595 Gorilla gorilla 101131683
9669 Mustela putorius furo 101686304 43179 Ictidomys tridecemlineatus 101974502
7897 Latimeria chalumnae 102346883 59463 Myotis lucifugus 102426942
10116 Rattus norvegicus 25483 7668 Strongylocentrotus purpuratus 373467
7227 Drosophila melanogaster 45285 9913 Bos taurus 540230
7070 Tribolium castaneum 641531 9544 Macaca mulatta 694227
9358 Choloepus hoffmanni ENSCHOG00000004913 9483 Callithrix jacchus ENSCJAG00000019138
10141 Cavia porcellus ENSCPOG00000003596 7955 Danio rerio ENSDARG00000006982
10020 Dipodomys ordii ENSDORG00000008104 9365 Erinaceus europaeus ENSEEUG00000012182
9371 Echinops telfairi ENSETEG00000018267 9685 Felis catus ENSFCAG00000031424
9785 Loxodonta africana ENSLAFG00000031082 9103 Meleagris gallopavo ENSMGAG00000003712
9258 Ornithorhynchus anatinus ENSOANG00000001111 9978 Ochotona princeps ENSOPRG00000007719
7757 Petromyzon marinus ENSPMAG00000003709 9601 Pongo abelii ENSPPYG00000016061
13735 Pelodiscus sinensis ENSPSIG00000010376 9598 Pan troglodytes ENSPTRG00000017548
132908 Pteropus vampyrus ENSPVAG00000006409 9305 Sarcophilus harrisii ENSSHAG00000009505
37347 Tupaia belangeri ENSTBEG00000014273 99883 Tetraodon nigroviridis ENSTNIG00000010999
31033 Takifugu rubripes ENSTRUG00000002318 9739 Tursiops truncatus ENSTTRG00000015120
8364 Xenopus tropicalis ENSXETG00000009168

Paralogs
ENSECAG00000020619