Basic Information
Gene ID 100987321
Gene Name MSX2
Full Name Homeobox protein MSX-2
Organism Pan paniscus [9597]

Cross Reference
UniProt A1YG93 UniGene NULL
PDB NULL OMIM NULL
KEGG pps:100987321 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003814060 Gene3D G3DSA:1.10.10.60 IPR009057 128 201 1.70e-25 Homeodomain-like
XP_003814060 Pfam PF00046 IPR001356 143 199 5.30e-22 Homeobox domain
XP_003814060 PRINTS PR00024 IPR020479 164 175 1.10e-06 Homeodomain, metazoa
XP_003814060 PRINTS PR00024 IPR020479 179 189 1.10e-06 Homeodomain, metazoa
XP_003814060 PRINTS PR00024 IPR020479 189 198 1.10e-06 Homeodomain, metazoa
XP_003814060 ProSitePatterns PS00027 IPR017970 175 198 - Homeobox, conserved site
XP_003814060 ProSiteProfiles PS50071 IPR001356 140 200 0.00e-00 Homeobox domain
XP_003814060 SMART SM00389 IPR001356 142 204 1.20e-27 Homeobox domain
XP_003814060 SUPERFAMILY SSF46689 IPR009057 121 201 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003814060 PF00046 3.4e-22 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003814060 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
XP_003814060 GO:0001649 biological_process osteoblast differentiation
XP_003814060 GO:0002063 biological_process chondrocyte development
XP_003814060 GO:0002076 biological_process osteoblast development
XP_003814060 GO:0003148 biological_process outflow tract septum morphogenesis
XP_003814060 GO:0003198 biological_process epithelial to mesenchymal transition involved in endocardial cushion formation
XP_003814060 GO:0003416 biological_process endochondral bone growth
XP_003814060 GO:0006351 biological_process transcription, DNA-templated
XP_003814060 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003814060 GO:0007275 biological_process multicellular organismal development
XP_003814060 GO:0008285 biological_process negative regulation of cell proliferation
XP_003814060 GO:0009952 biological_process anterior/posterior pattern specification
XP_003814060 GO:0023019 biological_process signal transduction involved in regulation of gene expression
XP_003814060 GO:0030513 biological_process positive regulation of BMP signaling pathway
XP_003814060 GO:0032792 biological_process negative regulation of CREB transcription factor activity
XP_003814060 GO:0035115 biological_process embryonic forelimb morphogenesis
XP_003814060 GO:0035116 biological_process embryonic hindlimb morphogenesis
XP_003814060 GO:0035313 biological_process wound healing, spreading of epidermal cells
XP_003814060 GO:0035880 biological_process embryonic nail plate morphogenesis
XP_003814060 GO:0042640 biological_process anagen
XP_003814060 GO:0043066 biological_process negative regulation of apoptotic process
XP_003814060 GO:0045599 biological_process negative regulation of fat cell differentiation
XP_003814060 GO:0045617 biological_process negative regulation of keratinocyte differentiation
XP_003814060 GO:0045669 biological_process positive regulation of osteoblast differentiation
XP_003814060 GO:0045892 biological_process negative regulation of transcription, DNA-templated
XP_003814060 GO:0051795 biological_process positive regulation of catagen
XP_003814060 GO:0060346 biological_process bone trabecula formation
XP_003814060 GO:0060364 biological_process frontal suture morphogenesis
XP_003814060 GO:0060444 biological_process branching involved in mammary gland duct morphogenesis
XP_003814060 GO:0061312 biological_process BMP signaling pathway involved in heart development
XP_003814060 GO:0070166 biological_process enamel mineralization
XP_003814060 GO:0071363 biological_process cellular response to growth factor stimulus
XP_003814060 GO:0071392 biological_process cellular response to estradiol stimulus
XP_003814060 GO:0090427 biological_process activation of meiosis
XP_003814060 GO:2000678 biological_process negative regulation of transcription regulatory region DNA binding
XP_003814060 GO:2001055 biological_process positive regulation of mesenchymal cell apoptotic process
XP_003814060 GO:0005634 cellular_component nucleus
XP_003814060 GO:0005667 cellular_component transcription factor complex
XP_003814060 GO:0005737 cellular_component cytoplasm
XP_003814060 GO:0003677 molecular_function DNA binding
XP_003814060 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003814060 GO:0003712 molecular_function transcription cofactor activity
XP_003814060 GO:0008134 molecular_function transcription factor binding
XP_003814060 GO:0043565 molecular_function sequence-specific DNA binding
XP_003814060 GO:0044212 molecular_function transcription regulatory region DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100026817 8090 Oryzias latipes 100049217
9796 Equus caballus 100058880 7425 Nasonia vitripennis 100114980
28377 Anolis carolinensis 100561295 7029 Acyrthosiphon pisum 100575011
61853 Nomascus leucogenys 100581634 400682 Amphimedon queenslandica 100631603
30195 Bombus terrestris 100649911 132113 Bombus impatiens 100741791
10029 Cricetulus griseus 100761249 7463 Apis florea 100868820
143995 Megachile rotundata 100881753 34638 Metaseiulus occidentalis 100900625
9555 Papio anubis 101008621 39432 Saimiri boliviensis 101033932
9669 Mustela putorius furo 101686304 7897 Latimeria chalumnae 102346883
10116 Rattus norvegicus 25483 7227 Drosophila melanogaster 45285
9913 Bos taurus 540230 7070 Tribolium castaneum 641531
9544 Macaca mulatta 694227 7460 Apis mellifera 724412
9358 Choloepus hoffmanni ENSCHOG00000004913 7719 Ciona intestinalis ENSCING00000009129
9483 Callithrix jacchus ENSCJAG00000019138 10141 Cavia porcellus ENSCPOG00000003596
7955 Danio rerio ENSDARG00000006982 10020 Dipodomys ordii ENSDORG00000008104
9371 Echinops telfairi ENSETEG00000018267 9685 Felis catus ENSFCAG00000031424
9785 Loxodonta africana ENSLAFG00000031082 9315 Macropus eugenii ENSMEUG00000005940
9103 Meleagris gallopavo ENSMGAG00000003712 9978 Ochotona princeps ENSOPRG00000007719
7757 Petromyzon marinus ENSPMAG00000003709 9601 Pongo abelii ENSPPYG00000016061
13735 Pelodiscus sinensis ENSPSIG00000010376 9598 Pan troglodytes ENSPTRG00000017548
132908 Pteropus vampyrus ENSPVAG00000006409 9305 Sarcophilus harrisii ENSSHAG00000009505
37347 Tupaia belangeri ENSTBEG00000014273 9739 Tursiops truncatus ENSTTRG00000015120
8364 Xenopus tropicalis ENSXETG00000009168 9595 Gorilla gorilla 101131683
43179 Ictidomys tridecemlineatus 101974502 59463 Myotis lucifugus 102426942
9365 Erinaceus europaeus ENSEEUG00000012182 9258 Ornithorhynchus anatinus ENSOANG00000001111