Basic Information
Gene ID ENSDARG00000004111
Gene Name esr1; akap12
Full Name Estrogen receptor
Organism Danio rerio [7955]

Cross Reference
UniProt A5PMH3 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSDARP00000024987 Gene3D G3DSA:1.10.565.10 IPR008946 257 287 2.00e-81 Nuclear hormone receptor, ligand-binding
ENSDARP00000024987 Gene3D G3DSA:1.10.565.10 IPR008946 330 566 2.00e-81 Nuclear hormone receptor, ligand-binding
ENSDARP00000024987 Gene3D G3DSA:3.30.50.10 IPR013088 203 256 2.30e-27 Zinc finger, NHR/GATA-type
ENSDARP00000024987 Pfam PF00104 IPR000536 357 543 3.60e-27 Nuclear hormone receptor, ligand-binding, core
ENSDARP00000024987 Pfam PF00105 IPR001628 202 270 6.80e-31 Zinc finger, nuclear hormone receptor-type
ENSDARP00000024987 Pfam PF02159 IPR001292 52 199 4.20e-41 Oestrogen receptor
ENSDARP00000024987 PIRSF PIRSF002527 IPR024178 57 616 0.00e-00 Oestrogen receptor/oestrogen-related receptor
ENSDARP00000024987 PIRSF PIRSF500101 IPR001292 10 620 0.00e-00 Oestrogen receptor
ENSDARP00000024987 PRINTS PR00047 IPR001628 203 219 9.10e-17 Zinc finger, nuclear hormone receptor-type
ENSDARP00000024987 PRINTS PR00047 IPR001628 219 234 9.10e-17 Zinc finger, nuclear hormone receptor-type
ENSDARP00000024987 PRINTS PR00047 IPR001628 252 260 9.10e-17 Zinc finger, nuclear hormone receptor-type
ENSDARP00000024987 PRINTS PR00047 IPR001628 260 268 9.10e-17 Zinc finger, nuclear hormone receptor-type
ENSDARP00000024987 PRINTS PR00398 IPR001723 264 274 4.20e-27 Steroid hormone receptor
ENSDARP00000024987 PRINTS PR00398 IPR001723 368 389 4.20e-27 Steroid hormone receptor
ENSDARP00000024987 PRINTS PR00398 IPR001723 389 405 4.20e-27 Steroid hormone receptor
ENSDARP00000024987 PRINTS PR00398 IPR001723 457 472 4.20e-27 Steroid hormone receptor
ENSDARP00000024987 PRINTS PR00398 IPR001723 525 542 4.20e-27 Steroid hormone receptor
ENSDARP00000024987 ProSitePatterns PS00031 IPR001628 203 229 - Zinc finger, nuclear hormone receptor-type
ENSDARP00000024987 ProSiteProfiles PS51030 IPR001628 200 275 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSDARP00000024987 SMART SM00399 IPR001628 200 271 3.40e-39 Zinc finger, nuclear hormone receptor-type
ENSDARP00000024987 SMART SM00430 IPR000536 367 537 9.00e-35 Nuclear hormone receptor, ligand-binding, core
ENSDARP00000024987 SUPERFAMILY SSF48508 IPR008946 327 566 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSDARP00000024987 PF02159 4.19997e-41 Oest_recep Oestrogen receptor
ENSDARP00000024987 PF00105 3.1e-31 zf-C4 Zinc finger, C4 type (two domains)
ENSDARP00000024987 PF00104 2.2e-27 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSDARP00000024987 GO:0006351 biological_process transcription, DNA-templated
ENSDARP00000024987 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSDARP00000024987 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSDARP00000024987 GO:0005634 cellular_component nucleus
ENSDARP00000024987 GO:0003677 molecular_function DNA binding
ENSDARP00000024987 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSDARP00000024987 GO:0003707 molecular_function steroid hormone receptor activity
ENSDARP00000024987 GO:0005496 molecular_function steroid binding
ENSDARP00000024987 GO:0008270 molecular_function zinc ion binding
ENSDARP00000024987 GO:0008289 molecular_function lipid binding
ENSDARP00000024987 GO:0030284 molecular_function estrogen receptor activity
ENSDARP00000024987 GO:0043565 molecular_function sequence-specific DNA binding
ENSDARP00000024987 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100027187 9555 Papio anubis 100303417
9986 Oryctolagus cuniculus 100351261 61853 Nomascus leucogenys 100580202
9597 Pan paniscus 100980011 10090 Mus musculus 13982
9615 Canis familiaris 403640 28377 Anolis carolinensis ENSACAG00000006213
9913 Bos taurus ENSBTAG00000007159 9483 Callithrix jacchus 100385918
9103 Meleagris gallopavo 100542782 10141 Cavia porcellus 100713276
10029 Cricetulus griseus 100768474 9669 Mustela putorius furo 101690352
8083 Xiphophorus maculatus 102235986 13735 Pelodiscus sinensis 102456765
9606 Homo sapiens 2099 9646 Ailuropoda melanoleuca ENSAMEG00000011072
9685 Felis catus ENSFCAG00000031492 69293 Gasterosteus aculeatus ENSGACG00000008711
9031 Gallus gallus ENSGALG00000012973 59463 Myotis lucifugus ENSMLUG00000014181
8090 Oryzias latipes ENSORLG00000014514 31033 Takifugu rubripes ENSTRUG00000018219
9478 Tarsius syrichta ENSTSYG00000006280 9739 Tursiops truncatus ENSTTRG00000002996
8364 Xenopus tropicalis ENSXETG00000012364 10020 Dipodomys ordii ENSDORG00000010443
9796 Equus caballus ENSECAG00000022441 9595 Gorilla gorilla ENSGGOG00000009678
8049 Gadus morhua ENSGMOG00000014898 9315 Macropus eugenii ENSMEUG00000003564
30611 Otolemur garnettii ENSOGAG00000012580 8128 Oreochromis niloticus ENSONIG00000013354
9978 Ochotona princeps ENSOPRG00000012663 132908 Pteropus vampyrus ENSPVAG00000001923
43179 Ictidomys tridecemlineatus ENSSTOG00000006748 37347 Tupaia belangeri ENSTBEG00000005946
59729 Taeniopygia guttata ENSTGUG00000011249 99883 Tetraodon nigroviridis ENSTNIG00000012264