Basic Information
Gene ID ENSXETG00000022348
Gene Name sox9
Full Name Transcription factor Sox-9
Organism Xenopus tropicalis [8364]

Cross Reference
UniProt F7C067 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSXETP00000048344 Gene3D G3DSA:1.10.30.10 IPR009071 104 149 6.30e-16 High mobility group box domain
ENSXETP00000048344 Pfam PF00505 IPR009071 106 149 8.90e-14 High mobility group box domain
ENSXETP00000048344 Pfam PF12444 IPR022151 23 96 3.70e-28 Sox developmental protein N-terminal
ENSXETP00000048344 ProSiteProfiles PS50118 IPR009071 106 145 0.00e-00 High mobility group box domain
ENSXETP00000048344 SMART SM00398 IPR009071 105 175 9.60e-12 High mobility group box domain
ENSXETP00000048344 SUPERFAMILY SSF47095 IPR009071 89 148 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSXETP00000048344 PF12444 3.7e-28 Sox_N Sox developmental protein N terminal
ENSXETP00000048344 PF00505 3.7e-14 HMG_box HMG (high mobility group) box

Gene Ontology Annotation
Protein Entry Name Space Description
ENSXETP00000048344 GO:0001501 biological_process skeletal system development
ENSXETP00000048344 GO:0001502 biological_process cartilage condensation
ENSXETP00000048344 GO:0001708 biological_process cell fate specification
ENSXETP00000048344 GO:0001837 biological_process epithelial to mesenchymal transition
ENSXETP00000048344 GO:0001894 biological_process tissue homeostasis
ENSXETP00000048344 GO:0001934 biological_process positive regulation of protein phosphorylation
ENSXETP00000048344 GO:0001942 biological_process hair follicle development
ENSXETP00000048344 GO:0002053 biological_process positive regulation of mesenchymal cell proliferation
ENSXETP00000048344 GO:0002683 biological_process negative regulation of immune system process
ENSXETP00000048344 GO:0003170 biological_process heart valve development
ENSXETP00000048344 GO:0003179 biological_process heart valve morphogenesis
ENSXETP00000048344 GO:0003203 biological_process endocardial cushion morphogenesis
ENSXETP00000048344 GO:0003413 biological_process chondrocyte differentiation involved in endochondral bone morphogenesis
ENSXETP00000048344 GO:0003415 biological_process chondrocyte hypertrophy
ENSXETP00000048344 GO:0006334 biological_process nucleosome assembly
ENSXETP00000048344 GO:0006338 biological_process chromatin remodeling
ENSXETP00000048344 GO:0006351 biological_process transcription, DNA-templated
ENSXETP00000048344 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSXETP00000048344 GO:0006366 biological_process transcription from RNA polymerase II promoter
ENSXETP00000048344 GO:0006461 biological_process protein complex assembly
ENSXETP00000048344 GO:0006468 biological_process protein phosphorylation
ENSXETP00000048344 GO:0007165 biological_process signal transduction
ENSXETP00000048344 GO:0007173 biological_process epidermal growth factor receptor signaling pathway
ENSXETP00000048344 GO:0007283 biological_process spermatogenesis
ENSXETP00000048344 GO:0008284 biological_process positive regulation of cell proliferation
ENSXETP00000048344 GO:0010564 biological_process regulation of cell cycle process
ENSXETP00000048344 GO:0010634 biological_process positive regulation of epithelial cell migration
ENSXETP00000048344 GO:0014068 biological_process positive regulation of phosphatidylinositol 3-kinase signaling
ENSXETP00000048344 GO:0019100 biological_process male germ-line sex determination
ENSXETP00000048344 GO:0019933 biological_process cAMP-mediated signaling
ENSXETP00000048344 GO:0030279 biological_process negative regulation of ossification
ENSXETP00000048344 GO:0030858 biological_process positive regulation of epithelial cell differentiation
ENSXETP00000048344 GO:0030916 biological_process otic vesicle formation
ENSXETP00000048344 GO:0032331 biological_process negative regulation of chondrocyte differentiation
ENSXETP00000048344 GO:0032332 biological_process positive regulation of chondrocyte differentiation
ENSXETP00000048344 GO:0035019 biological_process somatic stem cell maintenance
ENSXETP00000048344 GO:0042127 biological_process regulation of cell proliferation
ENSXETP00000048344 GO:0042981 biological_process regulation of apoptotic process
ENSXETP00000048344 GO:0043066 biological_process negative regulation of apoptotic process
ENSXETP00000048344 GO:0043491 biological_process protein kinase B signaling
ENSXETP00000048344 GO:0045662 biological_process negative regulation of myoblast differentiation
ENSXETP00000048344 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSXETP00000048344 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSXETP00000048344 GO:0046533 biological_process negative regulation of photoreceptor cell differentiation
ENSXETP00000048344 GO:0050679 biological_process positive regulation of epithelial cell proliferation
ENSXETP00000048344 GO:0050680 biological_process negative regulation of epithelial cell proliferation
ENSXETP00000048344 GO:0051216 biological_process cartilage development
ENSXETP00000048344 GO:0060008 biological_process Sertoli cell differentiation
ENSXETP00000048344 GO:0060041 biological_process retina development in camera-type eye
ENSXETP00000048344 GO:0060221 biological_process retinal rod cell differentiation
ENSXETP00000048344 GO:0060517 biological_process epithelial cell proliferation involved in prostatic bud elongation
ENSXETP00000048344 GO:0060729 biological_process intestinal epithelial structure maintenance
ENSXETP00000048344 GO:0060784 biological_process regulation of cell proliferation involved in tissue homeostasis
ENSXETP00000048344 GO:0061138 biological_process morphogenesis of a branching epithelium
ENSXETP00000048344 GO:0070168 biological_process negative regulation of biomineral tissue development
ENSXETP00000048344 GO:0070371 biological_process ERK1 and ERK2 cascade
ENSXETP00000048344 GO:0071260 biological_process cellular response to mechanical stimulus
ENSXETP00000048344 GO:0071364 biological_process cellular response to epidermal growth factor stimulus
ENSXETP00000048344 GO:0071504 biological_process cellular response to heparin
ENSXETP00000048344 GO:0072034 biological_process renal vesicle induction
ENSXETP00000048344 GO:0072289 biological_process metanephric nephron tubule formation
ENSXETP00000048344 GO:0090090 biological_process negative regulation of canonical Wnt signaling pathway
ENSXETP00000048344 GO:0090103 biological_process cochlea morphogenesis
ENSXETP00000048344 GO:0090184 biological_process positive regulation of kidney development
ENSXETP00000048344 GO:0090190 biological_process positive regulation of branching involved in ureteric bud morphogenesis
ENSXETP00000048344 GO:2000020 biological_process positive regulation of male gonad development
ENSXETP00000048344 GO:2000741 biological_process positive regulation of mesenchymal stem cell differentiation
ENSXETP00000048344 GO:0005634 cellular_component nucleus
ENSXETP00000048344 GO:0043234 cellular_component protein complex
ENSXETP00000048344 GO:0001046 molecular_function core promoter sequence-specific DNA binding
ENSXETP00000048344 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
ENSXETP00000048344 GO:0001158 molecular_function enhancer sequence-specific DNA binding
ENSXETP00000048344 GO:0003677 molecular_function DNA binding
ENSXETP00000048344 GO:0003682 molecular_function chromatin binding
ENSXETP00000048344 GO:0003705 molecular_function RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
ENSXETP00000048344 GO:0004672 molecular_function protein kinase activity
ENSXETP00000048344 GO:0035326 molecular_function enhancer binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9595 Gorilla gorilla 101135517 43179 Ictidomys tridecemlineatus 101970684
8083 Xiphophorus maculatus 102219562 9615 Canis familiaris ENSCAFG00000004374
9031 Gallus gallus ENSGALG00000012290 9785 Loxodonta africana ENSLAFG00000001445
9103 Meleagris gallopavo ENSMGAG00000006638 30608 Microcebus murinus ENSMICG00000013132
9544 Macaca mulatta ENSMMUG00000002412 9669 Mustela putorius furo ENSMPUG00000014303
61853 Nomascus leucogenys ENSNLEG00000002643 9978 Ochotona princeps ENSOPRG00000007860
8090 Oryzias latipes ENSORLG00000007960 9813 Procavia capensis ENSPCAG00000016336
13735 Pelodiscus sinensis ENSPSIG00000016802 132908 Pteropus vampyrus ENSPVAG00000010109
9823 Sus scrofa ENSSSCG00000017251 37347 Tupaia belangeri ENSTBEG00000000175
99883 Tetraodon nigroviridis ENSTNIG00000009759 30538 Vicugna pacos ENSVPAG00000000908
13616 Monodelphis domestica 100024115 9601 Pongo abelii 100452528
8128 Oreochromis niloticus 100693400 10141 Cavia porcellus 100725927
10029 Cricetulus griseus 100754443 9597 Pan paniscus 100970122
9555 Papio anubis 101003954 39432 Saimiri boliviensis 101044084
7897 Latimeria chalumnae 102351194 10116 Rattus norvegicus 29361
7955 Danio rerio 60641 28377 Anolis carolinensis ENSACAG00000008719
9646 Ailuropoda melanoleuca ENSAMEG00000016948 9483 Callithrix jacchus ENSCJAG00000000109
10020 Dipodomys ordii ENSDORG00000012440 9796 Equus caballus ENSECAG00000022037
9365 Erinaceus europaeus ENSEEUG00000011263 9371 Echinops telfairi ENSETEG00000020237
9685 Felis catus ENSFCAG00000015685 69293 Gasterosteus aculeatus ENSGACG00000011185
8049 Gadus morhua ENSGMOG00000009261 9315 Macropus eugenii ENSMEUG00000009986
59463 Myotis lucifugus ENSMLUG00000014317 9986 Oryctolagus cuniculus ENSOCUG00000011639
30611 Otolemur garnettii ENSOGAG00000027844 7757 Petromyzon marinus ENSPMAG00000010371
9598 Pan troglodytes ENSPTRG00000009592 9305 Sarcophilus harrisii ENSSHAG00000018176
31033 Takifugu rubripes ENSTRUG00000017157 9739 Tursiops truncatus ENSTTRG00000005687