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SEQPower provides statistical power analysis and sample size estimation for sequence-based association studies



Major Features

  • Power and sample size calculation for rare variant association study designs
  • Power comparison of rare variant association methods
  • Validation and evaluation of novel association tests

SEQPower Analysis Flowchart

Quick Start Guide!

Here is a short tutorial using SEQPower to perform power analysis. We encourage you to walk through this minimal example to get a feel of the software and assess its helpfulness.

How to Cite SEQPower

G. T. Wang, B. Li, R. L. P. Santos-Cortez, B. Peng and S. M. Leal, Power analysis and sample size estimation for sequence-based association studies. Bioinformatics. (2014) [pubmed]


Development of SEQPower was supported by the NHLBI Exome Sequencing Project, the Minority Health GRID project, and the Centers for Mendelian Genomics.


  • 2015.07.20 Release of SEQPower 1.1.0
    • What's new? >>
  • 2014.08.20 Release of SEQPower 1.0.1
    • What's new? >>
  • 2014.06.10 Release of SEQPower 1.0.0
  • 2014.01.22 Release of SEQPower 1.0 rc1
  • 2013.10.08 Release of SEQPower 1.0 beta
  • 2013.05.05 Initial public release, under project name RarePower
  • 2010.07.31 Project conceived