Basic Information
Gene ID ENSPTRG00000002949
Gene Name TCF7L2
Full Name Uncharacterized protein
Organism Pan troglodytes [9598]

Cross Reference
UniProt H2Q2K9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPTRP00000005208 Gene3D G3DSA:1.10.30.10 IPR009071 214 296 6.40e-29 High mobility group box domain
ENSPTRP00000005208 PANTHER PTHR10373 IPR024940 1 485 0.00e-00 Transcription factor TCF/LEF
ENSPTRP00000005208 PANTHER PTHR10373:SF26 IPR028773 1 485 0.00e-00 Transcription factor 7-like 2
ENSPTRP00000005208 Pfam PF00505 IPR009071 216 283 8.10e-22 High mobility group box domain
ENSPTRP00000005208 Pfam PF08347 IPR013558 12 125 5.80e-37 CTNNB1 binding, N-teminal
ENSPTRP00000005208 ProSiteProfiles PS50118 IPR009071 216 284 0.00e-00 High mobility group box domain
ENSPTRP00000005208 SMART SM00398 IPR009071 215 285 3.90e-25 High mobility group box domain
ENSPTRP00000005208 SUPERFAMILY SSF47095 IPR009071 215 296 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPTRP00000005208 PF08347 5.8e-37 CTNNB1_binding N-terminal CTNNB1 binding
ENSPTRP00000005208 PF00505 4.1e-22 HMG_box HMG (high mobility group) box
ENSPTRP00000005208 PF09011 7.8e-08 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPTRP00000005208 GO:0006351 biological_process transcription, DNA-templated
ENSPTRP00000005208 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSPTRP00000005208 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSPTRP00000005208 GO:0007275 biological_process multicellular organismal development
ENSPTRP00000005208 GO:0016055 biological_process Wnt signaling pathway
ENSPTRP00000005208 GO:0060070 biological_process canonical Wnt signaling pathway
ENSPTRP00000005208 GO:0005634 cellular_component nucleus
ENSPTRP00000005208 GO:0003677 molecular_function DNA binding
ENSPTRP00000005208 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPTRP00000005208 GO:0008013 molecular_function beta-catenin binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100120687 9597 Pan paniscus 100978424
9555 Papio anubis 101026705 7668 Strongylocentrotus purpuratus 373203
7227 Drosophila melanogaster 43769 28377 Anolis carolinensis ENSACAG00000010433
9646 Ailuropoda melanoleuca ENSAMEG00000015382 9483 Callithrix jacchus ENSCJAG00000018987
7955 Danio rerio ENSDARG00000004415 9361 Dasypus novemcinctus ENSDNOG00000012035
9796 Equus caballus ENSECAG00000024121 9371 Echinops telfairi ENSETEG00000018612
9315 Macropus eugenii ENSMEUG00000011191 30608 Microcebus murinus ENSMICG00000007510
9544 Macaca mulatta ENSMMUG00000022799 13616 Monodelphis domestica ENSMODG00000010133
9258 Ornithorhynchus anatinus ENSOANG00000001579 9978 Ochotona princeps ENSOPRG00000005139
8090 Oryzias latipes ENSORLG00000008387 9601 Pongo abelii ENSPPYG00000002661
7029 Acyrthosiphon pisum 100161896 6087 Hydra magnipapillata 100199257
10224 Saccoglossus kowalevskii 100303556 400682 Amphimedon queenslandica 100641322
34638 Metaseiulus occidentalis 100905988 39432 Saimiri boliviensis 101037011
13735 Pelodiscus sinensis 102459521 6239 Caenorhabditis elegans 171849
10090 Mus musculus 21416 7070 Tribolium castaneum 641465
9606 Homo sapiens 6934 9913 Bos taurus ENSBTAG00000021574
9615 Canis familiaris ENSCAFG00000011005 10141 Cavia porcellus ENSCPOG00000002152
51511 Ciona savignyi ENSCSAVG00000007833 10020 Dipodomys ordii ENSDORG00000011398
9365 Erinaceus europaeus ENSEEUG00000007595 9685 Felis catus ENSFCAG00000018774
8049 Gadus morhua ENSGMOG00000007406 7897 Latimeria chalumnae ENSLACG00000015707
9785 Loxodonta africana ENSLAFG00000018192 59463 Myotis lucifugus ENSMLUG00000008783
9669 Mustela putorius furo ENSMPUG00000002032 61853 Nomascus leucogenys ENSNLEG00000015863
9986 Oryctolagus cuniculus ENSOCUG00000008142 30611 Otolemur garnettii ENSOGAG00000014475
8128 Oreochromis niloticus ENSONIG00000016240 7757 Petromyzon marinus ENSPMAG00000004519
132908 Pteropus vampyrus ENSPVAG00000016688 10116 Rattus norvegicus ENSRNOG00000049232
9305 Sarcophilus harrisii ENSSHAG00000017344 9823 Sus scrofa ENSSSCG00000010638
43179 Ictidomys tridecemlineatus ENSSTOG00000006847 37347 Tupaia belangeri ENSTBEG00000002995
31033 Takifugu rubripes ENSTRUG00000012549 9478 Tarsius syrichta ENSTSYG00000012796
8364 Xenopus tropicalis ENSXETG00000018735 8083 Xiphophorus maculatus ENSXMAG00000014710
59729 Taeniopygia guttata ENSTGUG00000010805 99883 Tetraodon nigroviridis ENSTNIG00000010305
9739 Tursiops truncatus ENSTTRG00000002360 30538 Vicugna pacos ENSVPAG00000008158

Paralogs
461425