Basic Information
Gene ID ENSTSYG00000001081
Gene Name ENSTSYG00000001081
Full Name ENSTSYG00000001081
Organism Tarsius syrichta [9478]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSTSYP00000001003 Pfam PF08778 IPR014887 776 815 1.50e-22 HIF-1 alpha, transactivation domain, C-terminal
ENSTSYP00000001003 Pfam PF11413 IPR021537 539 571 4.70e-16 Hypoxia-inducible factor, alpha subunit
ENSTSYP00000001003 PRINTS PR01080 IPR001321 190 213 9.90e-48 Hypoxia-inducible factor-1 alpha
ENSTSYP00000001003 PRINTS PR01080 IPR001321 349 367 9.90e-48 Hypoxia-inducible factor-1 alpha
ENSTSYP00000001003 PRINTS PR01080 IPR001321 406 424 9.90e-48 Hypoxia-inducible factor-1 alpha
ENSTSYP00000001003 PRINTS PR01080 IPR001321 446 466 9.90e-48 Hypoxia-inducible factor-1 alpha
ENSTSYP00000001003 ProSiteProfiles PS50112 IPR000014 236 287 0.00e-00 PAS domain
ENSTSYP00000001003 ProSiteProfiles PS50888 IPR011598 6 59 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSTSYP00000001003 SMART SM00086 IPR001610 291 334 2.80e-10 PAC motif
ENSTSYP00000001003 SMART SM00091 IPR000014 219 285 8.20e-11 PAS domain
ENSTSYP00000001003 SMART SM00353 IPR011598 12 67 5.00e-10 Myc-type, basic helix-loop-helix (bHLH) domain
ENSTSYP00000001003 SUPERFAMILY SSF47459 IPR011598 4 59 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSTSYP00000001003 SUPERFAMILY SSF55785 IPR000014 231 331 0.00e-00 PAS domain
ENSTSYP00000001003 TIGRFAM TIGR00229 IPR000014 238 319 2.20e-08 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSTSYP00000001003 PF08778 8e-23 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
ENSTSYP00000001003 PF14598 2.1e-22 PAS_11 PAS domain
ENSTSYP00000001003 PF08447 5.4e-20 PAS_3 PAS fold
ENSTSYP00000001003 PF11413 2.2e-16 HIF-1 Hypoxia-inducible factor-1
ENSTSYP00000001003 PF13426 1.1e-07 PAS_9 PAS domain
ENSTSYP00000001003 PF00989 1.2e-07 PAS PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSTSYP00000001003 GO:0001666 biological_process response to hypoxia
ENSTSYP00000001003 GO:0006351 biological_process transcription, DNA-templated
ENSTSYP00000001003 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSTSYP00000001003 GO:0007165 biological_process signal transduction
ENSTSYP00000001003 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSTSYP00000001003 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSTSYP00000001003 GO:0071456 biological_process cellular response to hypoxia
ENSTSYP00000001003 GO:0005634 cellular_component nucleus
ENSTSYP00000001003 GO:0005737 cellular_component cytoplasm
ENSTSYP00000001003 GO:0003677 molecular_function DNA binding
ENSTSYP00000001003 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSTSYP00000001003 GO:0004871 molecular_function signal transducer activity
ENSTSYP00000001003 GO:0035035 molecular_function histone acetyltransferase binding
ENSTSYP00000001003 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100411678 8128 Oreochromis niloticus 100703737
7463 Apis florea 100864608 9597 Pan paniscus 100993223
9555 Papio anubis 100999094 39432 Saimiri boliviensis 101044689
9685 Felis catus 101083686 8083 Xiphophorus maculatus 102217674
7897 Latimeria chalumnae 102348279 7955 Danio rerio 393202
7668 Strongylocentrotus purpuratus 577801 7070 Tribolium castaneum 655772
28377 Anolis carolinensis ENSACAG00000016205 7719 Ciona intestinalis ENSCING00000002100
9361 Dasypus novemcinctus ENSDNOG00000017069 9796 Equus caballus ENSECAG00000015597
9365 Erinaceus europaeus ENSEEUG00000005910 9031 Gallus gallus ENSGALG00000011870
8049 Gadus morhua ENSGMOG00000010900 9785 Loxodonta africana ENSLAFG00000013410
9103 Meleagris gallopavo ENSMGAG00000013552 30608 Microcebus murinus ENSMICG00000002224
13616 Monodelphis domestica ENSMODG00000008760 9258 Ornithorhynchus anatinus ENSOANG00000009092
9986 Oryctolagus cuniculus ENSOCUG00000017741 30611 Otolemur garnettii ENSOGAG00000016112
9978 Ochotona princeps ENSOPRG00000007753 8090 Oryzias latipes ENSORLG00000002004
9813 Procavia capensis ENSPCAG00000011584 42254 Sorex araneus ENSSARG00000011198
43179 Ictidomys tridecemlineatus ENSSTOG00000004833 37347 Tupaia belangeri ENSTBEG00000011941
59729 Taeniopygia guttata ENSTGUG00000012978 99883 Tetraodon nigroviridis ENSTNIG00000009866
31033 Takifugu rubripes ENSTRUG00000012093 7029 Acyrthosiphon pisum 100167974
10224 Saccoglossus kowalevskii 100329032 9669 Mustela putorius furo 101692645
13735 Pelodiscus sinensis 102457736 9615 Canis familiaris 480348
9598 Pan troglodytes 746195 9646 Ailuropoda melanoleuca ENSAMEG00000003105
9358 Choloepus hoffmanni ENSCHOG00000008208 10141 Cavia porcellus ENSCPOG00000005317
51511 Ciona savignyi ENSCSAVG00000005768 10020 Dipodomys ordii ENSDORG00000004304
69293 Gasterosteus aculeatus ENSGACG00000008525 9595 Gorilla gorilla ENSGGOG00000003957
59463 Myotis lucifugus ENSMLUG00000015244 7757 Petromyzon marinus ENSPMAG00000009272
9601 Pongo abelii ENSPPYG00000005881 132908 Pteropus vampyrus ENSPVAG00000014497
10116 Rattus norvegicus ENSRNOG00000008292 9823 Sus scrofa ENSSSCG00000005096
8364 Xenopus tropicalis ENSXETG00000014449 9739 Tursiops truncatus ENSTTRG00000012558
30538 Vicugna pacos ENSVPAG00000002395