Jeff Layton wrote: [snip] > If you have the memory, why not make a RAM disk to store any > local information (I guess it depends on the size of the database). > However, have you seen the new motherboards from Tyan and > Supermicro that can handle up to 16 Gigs of DDR!? Very cool > possibilities now. An interesting idea. One issue I have, however, is the need to BLAST genomic vs genomic without masking for repetitive sequence. BLAST tackles this by storing a huge number of alignments and often delivers 80MB+ result files. Sure, I can parse the result on the fly before sending it back to the master node, but I have never paid attention to RAM usage under these circumstances. I will make a note to check during the next batch. In any event, RAM may be cheaper now, but a 40GB IDE or even high end SCSI is far, far cheaper than 16GB of DDR. -- Eric Engelhard - www.cvbig.org - www.sagresdiscovery.com