Hi All, I originally sumbitted this question to the Bioperl mailing list, but haven't received any replies. I wonder if anyone here can help ? Thanks, Andrew Hi, I'm having some problems getting the bioperl-ext to install under RHEL3 Update 5 for Opteron. I guess it's not strictly a Bioperl problem, but I figure someone here will have tried this before I and can offer some advice. The problem seems to be related to the Staden io_lib. Version 1.8.11 wouldn't compile, as the configure fails since it doesn't appear to undertsand Opterons. I looked around and found Verison 1.9.0 on Sourceforge and this appears to compile cleanly, however it doesn't look like it's left any .so files in /usr/local/lib (or anywhere else for that matter). It leaves the .a files, but no .so files. >From reading the staden::read makefile, this (and I'm guesing it's this ) causes the make process to fail and I can't build ext. I've copied the Read, os and configure header files into /usr/local/include. Apparently failure to do this is a common problem in the io_lib install process, but in this case, it's makes no difference. Has anyone on the list compiled the staden io_lib on Opteron ? If so, pointers to appropriate info/versions etc gratefully received. Thanks, Andrew Bioinformatics Advanced Scientific Computing, Animal Genetics and Genomics, PIRVic Attwood 475 Mickleham Road, Attwood, 3049 ph +61 3 92174342 mob 0413 009 761 ---------------- There are 10 kinds of people...those who understand binary and those who don't.